(+Equal Contributions, *Corresponding Authors:)

2025​

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60. Wang, Q., Zhao, Z., Yao, K., Cheng,  Y. L., Wong, D.S.H., Duo Wai-Chi Wong, James Chung-Wai Cheung, The Versatility of Biological Field-Effect Transistor-Based Biosensors (BioFETs) in Point-of-Care Diagnostics: Applications and Future Directions for Peritoneal Dialysis Monitoring, Biosensors, 15(3), 193

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59. Yin, B., Dodda, J. M.,* Wong, S.H.D,* Deen, G. R., Bate, J. S., Pachauri, A., Heidari, B. S., Kovářík, T., Luo, C., Tsai, S. W.*, Smart injectable hydrogels for periodontal regeneration: Recent Advancements in Biomaterials and Biofabrication Strategies​. Material Today Bio, 2025, 32, 101855

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58. Yao, K. Y., Lai, D. K. H., Lim, H. J., So, B. P. H., Chan, A. C. H., Yip, P. Y. M., Wong, D. W.-C.,* Dai, B., Zhao, X., Wong, S.H.D.,* Cheung, J.C.W.,* 2H-MoS2 Lubrication-Enhanced MWCNT nanocomposite for subtle Bio-Motion piezoresistive detection with deep learning integration. Materials & Design, 2025, 113861.

 

2024

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57. Yin, B., Wong, S.H.D.,* Deen, G.R., Bates, J.S., Pachauri, A., AlAnsari, R., Hájek, J., *Tsai, S.W., *Dodda, J.M. and Asmaki, N., 2024 (Under Review)

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56. Yin, B., Chen, J., Xiang G., Xu, Z., Yang, M.,* Wong, S.H.D.,* Multiscale and Stimuli-Responsive Biosensing in Biomedical Applications: Emerging Biomaterials Based on Aggregation-Induced Emission Luminogens Biosens. Bioelectron. 2025, 271, 117066 [Link]

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55. Yan, J., Yin, B., Zhang, Q., Li, C., Chen, J., Huang, H., Hao, J., Yi, C., Zhang, Y., Wong, S.H.D.,* Yang, M.,* A CRISPR-Cas12a-mediated dual-mode luminescence and colorimetric nucleic acid biosensing platform based on upconversion nanozyme, Biosens. Bioelectron. 2024, 270, 116963 [Link]

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54. +Li, C, +Yan, J., Yin, B., Zhang, Q., Huang, Y., Chen, J., Yang, M.,* Wong, S.H.D.*, Scaffold-free Efficient Light Harvesting Nanoparticles Based on One-pot Self-Assembly of Donor-Acceptor Aggregation Induced Emission Luminogens, ACS Applied Nano Materials, 2024, 7, 21, 24469–24476 [Link]

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53. +Zhang, Q., +Li, C., Yin, B., Yan, J., Gu, Y., Huang, Y., Chen, J., Lao, X., Hao, J., Yi, C., Zhou, Y., Cheung, J.C.W., Wong, S.H.D.*, Yang, M.,* A Biomimetic Upconversion Nanoreactors for Near-infrared Driven H2 Release to Inhibit Tauopathy in Alzheimer's Disease Therapy, Bioact. Mater. 2024, 42, 165-177 [Link] 

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52. Jiang, Y., Jiang, B., Wang, Z., Li, Y., Cheung, J.C.W., Yin, B.,* Wong, S.H.D.,* Nucleic Acid Armor: Fortifying RNA Therapeutics through Delivery and Targeting Innovations for Immunotherapy. Int. J. Mol. Sci. 2024, 25, 8888 [Link]

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51. +Wang, F, +Zhang, Q., Yang, M., Yin, B.,* Wong, S.H.D.,* Recent advances in optical techniques for dynamically probing cellular mechanobiology, Biomed. Eng. Commun. 2024, 3(3), 13 [Link]

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50. Wang, X., Xie, X., Li, Z., Zhang, X., Yang, B., Kang, H., Yung, P.S.H., Gao, Z., Wong, S.H.D*, Zhang, K.*, Bian, L.*, Catalysis-mediated dynamic ligand presentation regulates mechanosensing–metabolism coupling of stem cells, Nano Today 2024, 57, 102363 [Link]

 

49. +Huang, Y., +Zhang, Q., Lam, C.Y., Li, C., Chen, Y., Zhang, R., Zhong, Z., Yan, J., Chen, J., *Yin, B., *Wong, S.H.D., *Yang, M., An Aggregation-Induced Emission-Based Dual Emitting Nanoprobe for Detecting Intracellular pH and Unravelling Metabolic Variations in Differentiating Lymphocytes, ACS Nano 2024, 18, 24, 15935–15949 [Link]

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48. Wang, H., Chen, Z., Li, T., Xie, H., Yin, B., Wong, S.H.D., Shi, Y., Zhang, A.P., Optofluidic chip with directly printed polymer optical waveguide Mach-Zehnder interferometer sensors for label-free biodetection, Biomed. Opt. Express 2024, 15(5), 3240-3250  [Link] [Editor's Pick]

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47. Yin, B., Gosecka, M., Bodaghi, M., Crespy, D., Youssef, G., *Dodda, J. M., *Wong, S.H.D., Imran, A. B., Gosecki, M., Jobdeedamrong, A., Naniz, M. A., Zolfagharian, A., Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications, Chem. Eng. J., 2024, 487, 150403 [Link]

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46. Chen, J., Ho, W.K.H., Yin, B., Zhang, Q., Li, C., Yan, J., Huang, Y., Hao, J., Yi, C., Zhang, Y., *Wong, S.H.D., *Yang, Mo, Magnetic-responsive upconversion luminescence resonance energy transfer (LRET) biosensor for ultrasensitive detection of SARS-CoV-2 spike protein, Biosens. Bioelectron., 2024, 248, 115969 [Link]

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2023

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45. Yin, B., Zhang, Q., Yan, J., Huang, Y., Li, C., Chen, J., Wen, W., *Wong, S.H.D., *Yang, M., Nanomanipulation of Ligand  Nanogeometry Modulates Integrin/Clathrin-Mediated Adhesion and Endocytosis of Stem Cells, Nano Lett. 2023, (19), 9160–9169 [Link] (Selected Cover in Nano Letters Volume 23, Issue 19)

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44. Zou, S., Wang, F., Cheng, J*., Wong, S.H.D., Mechanism of cold plasma combined with glycation in altering IgE-binding capacity and digestion stability of tropomyosin from shrimp, J. Agric. Food Chem., 2023, 71 (42), 15796–15808 [Link]

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43. +Wong, S.H.D., +Yin, B., Li, L., Yuan, W., Zhang, Q., Xie, X., Tan, Y., Wong, N, *Zhang, K., *Bian, L., Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling, Sci. Adv. 2023, 9(27), eadg9593 [Link] (Featured in iNature Wechat subscription) (Feature in 高分子科技 WeChat subscriptions) (Featured in BioMed科技Wechat subscriptions) (Highlighted by Nature Reviews Cancer by Jain et al.)

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42. Yin, B., Wong, W.K., Ng, Y.M., Yang, M., *Leung, F.K.C., *Wong, S.H.D., Smart Design of Nanostructures for Boosting Tumor Immunogenicity in Cancer Immunotherapy, Pharmaceutics 2023, 15(5), 1427 [Link]

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41. Zhang, Q., Yin B., Huang, Y., Gu, Y., Yan, J., Chen, J., Li, C., Zhang, Y., *Wong, S.H.D., *Yang, M., A dual "turn-on" biosensor based on AIE effect and FRET for in situ detection of miR- 125b biomarker in early Alzheimer's disease, Biosens. Bioelectron., 2023, 230, 115270 [Link]

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40. Huang, Y., Yin, B., *Wong, S.H.D., Multicomponent Hydrogels in Clinical and Pharmaceutical Applications, Royal Society of Chemistry Books - Multicomponent Hydrogels: Smart Materials for Biomedical Applications, 2023, Chapter-14, 449-501 [Link]

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39. Yin, B.,  Ho, W. K. H., Xia, X. Y., Chan, C. K. W. Zhang, Q., Ng, Y. M., Lam, C. Y. K., Wang, J. F., *Yang, M., *Wong, S. H. D., A multilayered mesoporous gold nanoarchitecture for ultraeffective near-infrared light-controlled chemo/photothermal therapy for cancer guided by SERS imaging, Small, 2023, 19(6), 2206762 [Link] [Hot Topic: Mesoporous Materials (Small)] [Hot Topic: Surfaces and Interfaces (Advanced Materials Interfaces)] [Selected for Frontispiece in (Small 6/2023) Link] 

(As of March/April 2023 , this 🏆 highly cited paper received enough citations to place it in the top 1% of the academic field of Materials Science based on a highly cited threshold for the field and publication year.) (Featured in 化学与材料科学Wechat subscription)

Ranked within the top 10% of most-viewed papers published by Small in 2023

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38. Wong, S.H.D., Deen, G.R., Bates, J.S., Maiti, C, Lam, C.Y.K., Pachauri, A., AlAnsari, R., Belsky, P., Yoon, J., Dodda, J.M., Smart skin-adhesive patches: From design to biomedical applications, Adv. Funct. Mater., 2023, 2213560 [Link] [Hot topic: Flexible Electronics (Advanced Intelligent Systems)]

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2022

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37. Yin, B., Zhang, Q., Xia, X., Li, C., Ho, W.K.H., Yan, J., Huang, Y., Wu, H., Wang, P., Yi, C., Hao, J., Wang, J., Chen, H., *Wong, S.H.D., *Yang, M., A CRISPR-Cas12a integrated SERS nanoplatform with chimeric DNA/RNA hairpin guide for ultrasensitive nucleic acid detection, Theranostics, 2022, 12(13):5914-5930 [Link] (Featured in Theranostics WeChat subscription) (Feature in PolyU Vibrant@FENG - Issue 4, Major theme story 2023)

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36. Zhang, Q., Yin, B., Ma, L., Huang, Y., Shao, X., Li, C., Chu, Z., Hao, J., *Wong, S.H.D.; *Yang, M., An AIEgen/graphene oxide nanocomposite (AIEgen@GO)-based two-stage “turn-on” nucleic acid biosensor for rapid detection of SARS-CoV-2 viral sequence. Aggregate, 2022, 4(1), e195 (Featured in Aggregate WeChat subscription) (Feature in PolyU Vibrant@FENG - Issue 4, Major theme story 2023) [Link]

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35. Yin, B., Ho, W.K.H., Zhang, Q., Li, C., Huang, Y., Yan, J., Yang, H., Hao, J., *Wong, S.H.D., *Yang, M.,  Magnetic-Responsive Surface-Enhanced Raman Scattering Platform with Tunable Hot Spot for Ultrasensitive Virus Nucleic Acid Detection. ACS Appl. Mater. Interface, 2022, 14(3), 4714–4724 [Link] (Featured in PolyU Vibrant@FENG - Issue 3, Jul/Aug. 2022) [Link]

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34. +WONG, W. K.; +Yin, B.; Lam, C. Y. K.; *Tan, Z.; *Wong, S.H.D. The Interplay Between Epigenetic Regulation and CD8+ T cell Differentiation/Exhaustion for T cell Immunotherapy Front. Cell Dev. Biol. 2022, 9:783227 [Link]

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33. Zhang, Y., Wu H., Wang H., Yin B., Wong S.H.D., Zhang A.P., Tam H.Y., Ultraminiature optical fiber-tip directly-printed plasmonic biosensors for label-free biodetection, Biosens. Bioelectron, 2022, 218, 114761 [Link]

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32. Oh, J., Xia, X., Wong, W.K.R., Wong, S.H.D., Yuan, W., Wang, H., Lai, C.H.N., Tian, Y., Ho, Y.P., Zhang H., Zhang, Y., Li, G., Lin, Y.*, Bian, L.*, The effect of the nanoparticle shape on T cell activation, Small, 2022, 18 (36), 2107373 [Link]

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2021

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31. Yin, B.; Ni, J.; Witherel, C. E.; Yang, M., *Burdick, J. A.; *Wen, C.; *Wong, S.H.D. Harnessing Tissue-derived Extracellular Vesicles for Osteoarthritis Theranostics Theranostics, 2021, 12(1): 207-231 [Link]

(Featured in Theranostics WeChat subscription) (As of September/October 2022, this 🏆highly cited paper received enough citations to place it in the top 1% of the academic field of Clinical Medicine based on a highly cited threshold for the field and publication year. — Data from Essential Science Indicators)

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30. +Zhang, J.; +Wong, S. H. D.; Wu, X.; Lei, H,; Qin, M.; Shi, P.; *Wang, W.; *Bian, L.; *Cao, Y. Engineering Photo-responsive Ligand Tethers for Mechanical Regulation of Stem Cells Adv. Mater. 2021, 33(48): 2105765 [Link] (Feature in PolyU Vibrant@FENG - Issue 3, Jul/Aug. 2022)

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29. +Lam, C. Y. K.; +Zhang, Q.; Yin, B.; Huang, Y.; Wang, H.; *Yang M.; *Wong, S.H.D. Recent Advances in Two-dimensional Transition Metal Dichalcogenide Nanocomposites Biosensors for Virus Detection Before and During COVID-19 outbreak J. Compos. Sci. 2021, 5(7), 190 (Special issue review, highly accessed article) [Link]

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28. +WONG, W. K.; +Yin, B.; Rakhmatullina, A.; *Zhou, J.; *Wong, S.H.D. Engineering Advanced Dynamic Biomaterials to Optimize Adoptive T-cell Immunotherapy. Eng. Regen. 2021, 2, 70–81 (Invited perspective/review) [Link]

(Featured in EngineeredRegeneration再生工程 WeChat subscription)

 

27. +Wong, S. H. D.; +Xu X.; +Chen X.; Xin Y.; Xu L.; Lai C. H. N.; Oh J.; Wong W. K.; Wang X.; Han S.; You W.; Shuai X.; Wong N.; *Tan Y.; *Li D.; *Bian L. Manipulation of the nanoscale presentation of integrin ligand produces cancer cells with enhanced stemness and robust tumorigenicity. Nano Lett. 2021, 21, 7, 3225–3236 [Link]

(Featured in PolyU Vibrant@FENG - Issue 2, Dec. 2021)

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26. +Yang, B.; +Wei, K; Loebel, C.; Zhang, K.; Feng, Q; Li, R.; Wong S.H.D.; Xu, X.; Lau, C.; Chen, X.; Zhao, P.; Yin, C; Professor Burdick, J.; *Wang, Yi; *Bian, L. Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics Nat. Comm. 2021, 12 (1), 1-13 [Link]

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25. Huang, J.; Yang, B.; Peng, Y.; Huang, J.; Wong, S. H. D.; Bian, L.; *Zhu K.; *Shuai X.; *Han S. Nanomedicine-Boosting Tumor Immunogenicity for Enhanced Immunotherapy, Adv. Funct. Mater. 2021, 202011171 [Link]

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2020

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+Wong, W.K.R.; +Wong, S.H.D.; *Bian, L. Long-Term Detection of Oncogenic MicroRNA in Living Human Cancer Cells by Gold@Polydopamine–Shell Nanoprobe. ACS Biomater. Sci. Eng., 2020, 6, 7, 3778–3783 [Link]

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24. Wong, S.H.D.; Wong, W.K.R.; Lai, N.C.H.; Oh, J.; Li, Z.; Chen, X.; Yuan, W.; *Bian, L. Soft polymeric matrix as a macroscopic cage for magnetically modulating reversible nanoscale ligand presentation. Nano Lett., 2020, 20, 5, 3207-3216 [Link] 

(Featured in 高分子科技 WeChat subscriptions)

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23. +Chen, X.; +Lai, N.C.H.; +Wei, K.; Li, R.; Cui, M.; Yang, B.; Wong, S.H.D.; Deng, Y.; Li, J.; Shuai, X.; *Bian, L. Biomimetic presentation of cryptic ligands via single-chain nanogels for synergistic regulation of stem cells". ACS Nano 2020, 14, 4, 4027–4035 [Link]

(Featured in 納米人 WeChat subscriptions)

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2019

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22. Yin, B., Chan, C.K.W., Liu, S., Hong, H., Wong, S.H.D., Lee, L.K.C., Ho, L.W.C., Zhang, L., Leung, K.C.F., Choi, P.C.L., *Bian, L., *Tian, X.Y., *Chan M.N., and *Choi C.H.J., Intrapulmonary Cellular-Level Distribution of Inhaled Nanoparticles with Defined Functional Groups and Its Correlations with Protein Corona and Inflammatory Response. ACS Nano, 2019, 13(12): 14048-14069. [Link]

(Featured in 納米人 WeChat subscriptions)

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21. Chen, X.; Li, R; Wong, S.H.D.; Wei, K.; et al.; Xia, J.; Chen, G.; Li, G.; *Bian, L. Conformational manipulation of scale-up prepared single-chain polymeric nanogels for multiscale regulation of cells, Nat. Comm., 2019, 10: 2705 [Link]

(Featured in 高分子科技 WeChat subscriptions)

(Highlighted by CUHK communications and public relations office)

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20. +Kang, H.; +Wong, S.H.D.; Pan, Q..; Li, G.; *Bian, L., Anisotropic ligand nanogeometry modulates the adhesion and polarization state of macrophages, Nano Lett., 2019, 19(3): 1963-1975 [Link]

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19. +Wong, S.H.D.; +Yin, B.; Lin S.; Yang, B.; Li, R.; Feng, F.; Yang, H.; Zhang, L.; Yang, Z.; Li, G.; *Choi, C. H.; *Bian, L., Anisotropic nanoscale presentation of cell adhesion ligand enhances the recruitment of diverse integrins in adhesion structures and mechanosensing-dependent differentiation of stem cells, Adv. Funct. Mater., 2019, 29 (8): 1806822 [Link]

Highlighted by Nat. Rev. Bioeng. 2024 "Nanoscale anisotropy for biomedical applications" Figure 3b [Link]

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2018

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18. +Kang, H.; Jung, H.J.; Kim, S.K.; Wong, S.H.D.; Lin, S.; Li, G.; Dravid, V.; *Bian, L. Magnetic manipulation of reversible nanocaging controls in vivo adhesion and polarization of macrophages, ACS Nano, 2018, 12(6): 5978-5994. [Link]

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17. +Yin, C.; +Wen, G.; Liu, C.; Yang, B.; Lin, S.; Huang, J.; Zhao, P.; Wong, S.H.D., Zhang, K.; Chen, X.; Li, G.; Jiang, X.; *Pu, K.; *Wang, L.; *Bian, L. Organic Semiconducting Polymer Nanoparticles for Photoacoustic Labeling and Tracking of Stem Cells in the Second Near-Infrared Window. ACS Nano, 2018, 12 (12): 12201–2211. [Link]

(Featured in 材料牛cailiaoniu)

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16. +Kang, H.; +Zhang, K.; Pan, Q.; Lin, S.; Wong, S.H.D.; Li, J.; Lee, Y. W.; Yang, B.; Han, F.; *Li, B.; *Bian, L., Remote control of intracellular calcium using upconversion nanotransducers regulates stem cell differentiation in vivo, Adv. Funct. Mater., 2018, 28 (41): 201802642. [Link]

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15. Li, J.; Lee, Y. W.; Wu, T.; Leung, Y.T.C; Xu, J.; Wong, S.H.D.; Li, R.; *Li, G.; *Tang, B.Z.; *Bian, L., Detection of Matrix Metallopeptidase 13 for Monitoring Stem Cell Differentiation and Early Diagnosis of Osteoarthritis by Fluorescent Light‐Up Probes with Aggregation‐Induced Emission Characteristics, Adv. Biosys., 2018, 2(10): 1800010 [Link]

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14. Gao S., Tung W.T., S.H.D. Wong, Bian L., *Zhang A., Direct optical micropatterning of poly (dimethylsiloxane) for microfluidic devices J. Micromech. Microeng. 28 (9), 095011 [Link]

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13. +Kang, H.; Jung, H.J.; Kim, S.K.; Wong, S.H.D.; Lin, S.; Li, G.; Dravid, V.; *Bian, L., Magnetic Manipulation of Reversible Nanocaging Controls In Vivo Adhesion and Polarization of Macrophages, ACS Nano, 2018, 12 (6): 5978–994. [Link]

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12. +Li, R.; +Li, J.; Xu, J.; Wong, S.H.D.; Chen, X.; Yuan, W.; *Bian, L. Multiscale reconstruction of a synthetic biomimetic micro-niche for enhancing and monitoring the differentiation of stem cells. Biomater., 2018,173: 87-99 [Link]

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11. +Kang, H.; + Jung, H.J.; Wong, S.H.D.; Kim, S.K.; Lin, S.; Chan, K.F.; Zhang, L.; Li, G.; Dravid, V.; *Bian, L. Remote control of heterodimeric magnetic nanoswitch regulates the adhesion and differentiation of stem cells. J. Am. Chem. Soc., 2018;140 (18): 5909-5913. [Link]

Featured in the JACS Spotlight​

Published in 2019 JACS Young Investigators Virtual Issue

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10. +Kang, H.; +Zhang, K.; Wong, S.H.D.; Han, H.; Li, B.; Liming; *Bian, L. Near-infrared light-controlled regulation of intracellular calcium to modulate macrophage polarization. Biomater., 2018, 178:681-696 [Link]

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2017

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9. Zhao, P.; Wei, K.; Feng, Q.; Chen, H.; Wong, S.H.D.; Chen, X.; *Bian, L. Mussel-mimetic hydrogels with defined cross-linkers achieved by controlled catechol dimerization exhibiting tough adhesion for wet biological tissues. Chem. Comm., 2017, 53: 12000-12003. [Link]

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8. +Kang, H.; +Kim, S.; Wong, S.H.D.; Jung, H.J.; Lin, Si.; Zou, K.; Li, R.; Li, G.; *Dravid, V.; *Bian, L. Remote manipulation of ligand nano-oscillations regulates adhesion and polarization of macrophages in vivo. Nano Lett., 2017, 17 (10): 6415-6427 [Link]

(Featured in 高分子科技 WeChat subscriptions)

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7. +Kang, H.; +Wong, S.H.D.; Yan, X.; Jung, H.J.; King, S.K.; Lin, Si.; Wei, K.; Li, G.; *Dravid, V.; *Bian, L. Remote control of multi-Modal nanoscale ligand oscillations regulates stem cell adhesion and differentiation, ACS Nano, 2017, 11(10): 9636-9649 [Link]

(Featured in 高分子科技 WeChat subscriptions)

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6. +Wong, S.H.D.; +Li, J.; Yan, X.; Wang, B., Zhang, L.; *Bian, L. Magnetically tuning tether mobility of integrin ligand regulates adhesion, spreading, and differentiation of stem cells, Nano Lett., 2017, 17 (3): 1685-1695 [Link]

(Featured in 高分子科技 WeChat subscriptions)

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5. +Li, R.; +Xu, J.; Wong, S.H.D.; Li, J.; Zhao, P.; *Bian, L.; Self-assembled N-cadherin mimetic peptide hydrogels promote the chondrogenesis of mesenchymal stem cells through inhibition of canonical Wnt/β-catenin signaling. Biomaterials, 2017, 145: 33-43. [Link]

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4. +Ouyang, X.; +Zhang, K.; Wu, J.; Wong, S.H.D.; Feng, Q.; *Bian, L.; *Zhang, A. Optical μ-Printing of Cellular-Scale Microscaffold Arrays for 3D Cell Culture, Sci. Rep., 2017, 7 (1): 8880 [Link]

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3. Li, J.; Yan, X.; Leung, Y.T.C; Wong, S.H.D.; Xu, J.; Li, R.; Zhao, Y.; Yung, Y.Y.C; Zhao, E.; *Tang, B.Z.; *Bian, L. Photo-controlled siRNA delivery and biomarker-triggered AIEgen emission by upconversion NaYF4:Yb3+Tm3+@SiO2 nanoparticles for inducing and monitoring stem cell differentiation, ACS Appl. Mater. Interfaces, 2017, 11 (25): 22074-22084 [Link]

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2016

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2. +Li, J.; +Lee, Y. W.; Wu, T.; Xu, J.; Zhang, K.; Wong, S.H.D.; Li, R.; *Li, G.; *Bian, L. Near-infrared light-triggered release of small molecules for controlled differentiation and long-term tracking of stem cells in vivo using upconversion nanoparticles. Biomaterials, 2016, 110: 1-10 [Link]

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1. Shaorui Gao, Wing-Tai Tung, Wong, S.H.D, Liming Bian, *A Ping Zhang. Direct optical patterning of poly (dimethylsiloxane) microstructures for microfluidic chips. AOMATT 2016 Oct; 96850X-96850X-6 [Link]